Biomedical Data Analysis Platform

Quality Filtering: Loads CheckM results; excludes bins below user-defined thresholds.
Pairwise Comparison: Computes ANI between all passing genomes using fastANI (default) or MUMmer.
Clustering: Groups genomes exceeding ANI threshold into clusters via greedy algorithm.
Representative Selection: Picks best genome per cluster based on weighted score (completeness − 5×contamination + 0.5×size).
Output: Dereplicated genome set, clustering table, and comparison plots.

MAGs

Cluster_scoring.pdf

Primary_clustering_dendrogram.pdf

v1.0: Process construction, complete the basic process of dereplicating MAGs

1. Select the application 'de-replicate'
2. Click on the 'Analysis' button
3. Click on the 'drep'
4. Fll in the request parameters

dRep compare output_dir -g *.fa --genomeInfo checkm.tab [OPTIONS]

Parameter	Description
`-cov`	Minimum alignment coverage fraction (default: 0.85).
`-comp`	Min completeness % to include (default: 75).
`-con`	Max contamination % to include (default: 25).
`-sa`	Skip ANI computation; only filter by quality.
`-p`	Threads for ANI calculations.